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Because the peptide is cleared within a couple of hours, the pituitary gland is not subjected to constant, exhausting stimulation
However, the delayed gastric emptying associated with GLP-1 RAs complicates these traditional protocols and introduces a potential risk for residual gastric contents (RGC) and aspiration, even when patients adhere to the recommended fasting times (Joshi et al
In 2020, the U.S
Long-Term Outcomes (After 1 Year) Long-term adherence to semaglutide treatment can lead to remarkable and sustained weight loss
A small number of patients report mild reactions including nausea, slight discomfort at the injection site, or temporary tiredness
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