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2017;9(7):E686
This process is crucial because superoxide anions are among the first ROS to be produced during oxidative stress, particularly in mitochondria, which are key sources of ROS in sperm cells
Causes and consequences of oxidative stress in spermatozoa
And the early data support that logic
Following deposition, these crystals trigger an inflammatory cascade by activating the innate immune system (e.g., macrophages and neutrophils)
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