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This stimulant approach has been used since the 1950s for short-term weight management, typically limited to 12 weeks or less due to tolerance and potential dependence concerns
To understand what that means for safety, see the treatment options section
[12] [21] Importantly, the absolute amount of muscle lost correlates strongly with total weight losspatients losing more weight inevitably lose more lean mass in absolute terms, but the proportion remains relatively stable
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Its activity is mediated through copper transport, gene modulation, and interaction with extracellular matrix components
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