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Feedback / Questions cagrilintide/semaglutide (CagriSema) - Novo Nordisk CagriSema: Data from P3 REDEFINE 4 trial (NCT06131437) for obesity in 2026 (Novo Nordisk) - May 8, 2025 - Q1 2025 Results P3 data Obesity May 8, 2025 SHARE THIS Print Email More sharing Reddit StumbleUpon Delicious

10.1073/pnas.1017099108 Proc

Matthew Weiner, weight regain after VSG occurs in approximately 50% of patients, though some studies suggest the rate could be as high as 76%

Importantly, some patients taking the highest dose of oral semaglutide in trials achieved up to 22% weight loss, bringing results closer to what has previously only been associated with injectable GLP-1 treatments

Studies have also found that NAC may be effective in treating addiction and substance abuse