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Lin L, Du T, Huang J, Huang LL, Yang DZ
Chronic activation of microglia is associated with protein degradation, mitochondria dysfunction, and defects of axonal transport and apoptosis, which adversely affect neuronal function and lead to cell death (49)
Methods: We use mathematical models for hepatic glutathione metabolism, including one-carbon metabolism and acetaminophen detoxification, to investigate how the activation of certain enzymes by estradiol leads to dramatic changes in reaction velocities and metabolite concentrations
However, when it comes to supplementation, not all forms of glutathione are created equal