Both promise to make weight loss medications like semaglutide or tirzepatide accessible without the sky-high prices of brand-name prescriptions
Liposomal glutathione is widely considered a more effective option for supplementation
The liraglutide SmPC, for example, advises considering discontinuation if a clinically relevant sustained increase in resting heart rate is observed
These findings highlight the potential of plasma MOTS-c as a biomarker for monitoring insulin sensitivity, particularly in pre-diabetic lean individuals, where changes in MOTS-c levels could serve as an early indicator of insulin resistance
While GLP-1 therapies have significantly improved the management of both DM2 and obesity, several challenges remain, including patient variability in response, gastrointestinal side effects, cost considerations, and long-term adherence