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Individuals with a history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 should avoid GLP-1 receptor agonists

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Several HSP90 inhibitors, including 17-DMAG (alvespimycin), 17-AAG (tanespimycin), ganetespib and geldanamycin, exhibit senolytic effects across multiple senescent cell types through distinct, cell-type-specific mechanisms

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