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Consequently, VRK2 expression emerges as a dual-function biomarker: its targeted inhibition shows therapeutic efficacy in VRK2-high malignancies, while its deficiency serves as a predictive indicator for metabolic-targeted interventions

Therefore, documenting an Nnt WT genotype in C57BL/6 mice does not provide proof that their glucose tolerance is as good as in C57BL/6N mice

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This amount helps maintain glutathione in its active, "reduced" state and prevents it from being depleted too quickly by oxidative stress

10.1016/j.cell.2004.12.035 Cell 56 LiD.LiuX.LinL.HouJ.LiN.WangC.et al (2011)