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For various reasons physicians may be reluctant to prescribe these medications, however with a thoughtful and respectful discussion, you may be able to advocate for yourself for their use
PMCID: PMC2980962
If you want to make your skin lighter, fade the melasma, or have any skin discoloration problem, then you are a good candidate
We can check for heavy metals like lead
Specifically, IL-22 receptor activation on brain endothelial cells increases tight junction protein expression and endothelial cell proliferation, thus reducing inflammation-driven BBB permeability [205]
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