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Both medications are glucagon-like peptide-1 (GLP-1) receptor agonists, though tirzepatide also activates GIP receptors, which may contribute to slightly stronger average weight loss results in clinical trials
Zhao G, Lu G, Fan H, Wei L, Yu Q, Li M, et al
doi: 10.1016/S01406736(23)01200-X 105 WaddenTAChaoAMMachineniSKushnerRArdJSrivastavaGet al
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