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The interaction between autophagy and SIPS was analyzed using pharmacological autophagy modulators
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Histopathologic scoring for the liver was performed by the following criteria: degeneration of hepatocytes, vascular congestion and sinusoidal dilatation, inflammatory cell infiltration and the number of activated Kupffer cells
Treatment with NR or the PARP inhibitor Olaparib also improved mitochondrial morphology in aged nematodes and mammalian muscle cells during proteotoxic stress 114
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