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Metformin remains the first-line treatment for most people with type 2 diabetes, whilst canagliflozin is typically added when metformin alone is insufficient or used when metformin is not tolerated
Rare but serious complications associated with GLP-1 receptor agonists include pancreatitis, which can occur regardless of gallbladder status
GHK-Cu appears to be safe, although extremely high doses may drop blood pressure to dangerously low levels
Glucocorticoids suppress GLP-1 secretion: possible contribution to their diabetogenic effects
Retatrutide : Not yet submitted for regulatory approval
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