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Side effects are typically mild and may include slight bruising at the injection site, a cooling sensation, or a metallic taste (especially with certain vitamins)
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Consequently, individuals do not exhibit warning signs of overdose, such as vomiting or loss of consciousness, allowing blood alcohol concentration (BAC) to reach lethal levels unnoticed
3,5 In early T2DM managed with lifestyle alone, orforglipron lowered glycated hemoglobin A1c (HbA1c) by -1.24 to -1.48 percentage points over 40 weeks as compared to -0.41 with placebo, with no severe hypoglycemia reported and weight reduction ranging from 4.5% to 7.6%, 3 which led to mean HbA1c levels of 6.5-6.7%
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