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We also explored several other known regulators of PGC1 activity that are altered in response to 5FU treatment in HCT116, including NRF2, reactive oxygen species and PPAR, but none of these prevented PGC1-driven increases in mitochondrial mass
They are associated with oxidative stress, even though the causes differ
Signs include lip/tongue numbness, dizziness, visual disturbances, and progressing to seizures, respiratory depression, and cardiac arrest
Reduces body pigmentation and dark patches
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