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Brattstrm L, Landgren F, Israelsson B, Lindgren A, Hultberg B, Andersson A, Cuskelly G, McNulty H, Strain SS, McPartlin J, Weir DG, Scott JM, den Heijer M, Brouwer IA, Blom HJ, Bos GMJ, Spaans A, Rosendaal FR, Thomas CMG, Haak HL, Wijermans PW, Gerrits WBJ, Naurath HJ, and Joosten E (1998)
Science 330 , 13441348 (2010)
A recent data science evidence-based approach to determine the top ten ingredients in oral skin supplements (from 71,000 dietary ingredients of which 1781 were found to have at least one skin-related publication assessed in human clinical trials) found that collagen had the most published human skin health-related data, followed by specific antioxidants (especially from natural sources or products) [25]
Similarly, IRE1 dysregulation has been observed in tauopathies, PrD, and HD, highlighting its role in neurotoxicity, whereas ATF6 dysfunction exacerbates protein aggregation and has been linked to FTD and tauopathies
Promotes muscle tone
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