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Environ Sci Pollut Res Int 29:3819838211

9 Conclusions Preclinical studies show clear effects of GLP-1 and GIP receptor agonists in protecting neurons, normalizing energy utilization, protecting synaptic activity and cognition in AD, and protecting motor control in PD

A 20% increase in a hormone with a 2-minute half-life is fundamentally different from days-long pharmaceutical concentrations, regardless of pathway similarity

GLP-1RAs are synthetic molecules that mimic the effects of the naturally-occurring GLP-1 hormone, including increasing insulin secretion and slowing gastric emptying

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