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Curr Epidemiol Rep
The Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF-JAK) /STAT5- CCAAT/enhancer-binding protein (C/EBP) pathway can activate Acod1 to produce itaconate, mediating Nuclear factor erythroid 2related factor 2 (Nrf2)-dependent ferroptosis resistance and maintaining TIN persistence [48]
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IV drip therapy works from the inside out, so the changes are gradual rather than instant
Tregear S, Reston J, Schoelles K, Phillips B
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