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Some patients may be trained to manage their own injections at home, but this should only be done with proper instruction and supervision
Similar to scrapie, -synuclein pathology spreads in the peripheral and enteric nervous systems, then to CNS, whereas Alzheimers tau pathology propagates within the CNS only, beginning in the brainstem then involving cortical areas in a characteristic pattern (De La-Rocque et al., 2021)
p16 is crucial for maintaining senescence by regulating Rb protein phosphorylation to inhibit cell division 9
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Additionally, B12 deficiency can cause mood disorders like depression, which may contribute to emotional eating or a lack of motivation to maintain a healthy lifestyle, further impacting weight
