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Whereas, mouse GST M1-1 protects cells against both UV-and H2O2-induced cell death and binds to apoptosis signal-regulating kinase 1 (ASK1), inhibits its kinase activity [16]

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Cagrilintide works at microgram-level potency (2.4 mg maintenance), while retatrutide requires milligram-level doses up to 12 mg