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Presented for research literature review only Chrudinov M et al
would require billions of dollars and several years, offering no immediate relief for shortages or price increases
Side effects are uncommon and typically limited to mild injection site reactions
In the NATHAN 1 study, which included 460 patients with diabetes and mild-to-moderate, predominantly asymptomatic DPN, treatment with 600 mg of ALA daily for 4 years resulted in a reduction of the NIS by at least two points compared with placebo [68]
All the three doses of TZP confirmed an important decrease in HbA 1c and BW
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