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Indikationen Schubfrmig remittierende Multiple Sklerose (RRMS) Colitis ulcerosa (CU) Wirkmechanismus Modulator der Sphingosin-1-Phosphat (S1P)-Rezeptorsubtypen 1 und 5 Fhrt zu Lymphozytenretention in lymphoiden Geweben Wirkung vermutlich durch verringerte Lymphozytenmigration in ZNS/Darm Nebenwirkungen Nasopharyngitis u.a

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1 patient (1.3%) was overweight and changed category to obese