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Wegovy, in particular, is FDA-approved for weight loss in adults with obesity or overweight, and has shown consistent, proven results in clinical studies, with patients achieving significant weight reduction when combined with a reduced-calorie diet and increased physical activity
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Injections carry risks including nerve damage, kidney stress, allergic reactions, and in rare cases, liver abnormalities
Other GLP-1s may be considered off-label when clinically appropriate
significant excess skin typically requires surgical body contouring
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