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Contrary to normal smokers, COPD patients have defects in DNA repair, as documented by very low expression of the double-stranded repair protein Ku86 (Caramori et al

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Batch: GF-BPC10-B241 Key analytical results include: Assay Content: 10.71 mg Identification Retention Time: 0.998 Identification Spectrum: 996 Purity: greater than 99.8 percent Bacterial Endotoxins: 0.0120 EU per mg Total Aerobic Microbial Count: not detected Total Yeast and Mold Count: not detected Independent heavy metal screening confirmed no detectable levels of arsenic, cadmium, cobalt, lead, nickel, mercury or vanadium

Tissues were lysed by transferring them to pre-filled bead mill tubes (Fisher Scientific, 15-340-154) containing lysis buffer (Tris-HCl 100 mM and 0.5% Triton X-100, pH 8) containing Halt Protease and Phosphatase Inhibitor cocktail and homogenized using a bead mill (VWR) for 10 s