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Tirzepatides 5 mg, 10 mg, and 15 mg doses showed A1C reductions of 2.01, 2.24 and 2.30, respectively, surpassing semaglutides 1.86 reduction at the 1 mg dose
If gastrointestinal symptoms are problematic, adjusting the timing may be considered, with reassessment after several weeks
J Clin Invest 122(1):153162 Kim JD, Yoon NA, Jin S, Diano S (2019) Microglial UCP2 Mediates Inflammation and Obesity Induced by High-Fat Feeding
You might pause dose increases, return to a lower dose, or try switching to a different medication altogether
Sattar N, Lee MMY, Kristensen SL, Branch KRH, Del Prato S, Khurmi NS, Lam CSP, Lopes RD, McMurray JJV, Pratley RE, et al
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