Peptides like GHK-Cu and KPV inhibit NF-kB activation, reducing inflammatory markers by up to 60 percent in some studies
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underpowered, not double-blinded, not placebo-controlled and disparities in iodine intake were not considered ( Reference Wichman, Bonnema and Hegedus 88 , Reference van Zuuren, Albusta and Fedorowicz 89 , Reference Duntas and Benvenga 91 )
These molecular changes correlated with clinical motor improvements, suggesting a potential disease-modifying effect consistent with other trials showing both motor and cognitive benefits as well as biomarker evidence of enhanced insulin and neurotrophic signaling [32, 55]