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contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2), pancreatitis (discontinue if suspected), gallbladder disease, and acute kidney injury secondary to dehydration from gastrointestinal side effects

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Maximal reductions of at least 20% were seen in 26% of tirzepatide-treated patients, versus 12% of semaglutide-treated patients

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