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studies in kidney tissue and in animal models showed a reduction of NF-kB activity after the administration of exendin-4 [43, 44]
Missing data for the trial product estimand were handled through multiple imputation using the Markov Chain Monte Carlo method, assuming that non-adherent participants would have responded similarly to adherent participants within the same treatment arm
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Moreover, in NAFLD, deficits in both immediate and delayed memory have been consistently observed, with the severity of liver fibrosis positively correlated with cognitive dysfunction [23]
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