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For people who have spent years or decades fighting food impulses, this quiet mind around eating feels transformative even before the scale shows dramatic numbers
This additional impact on body weight is one reason physicians may titrate patients up to 3.0 mg or 4.5 mg when blood-sugar control and weight loss are treatment goals
GLP-1 agonists may also directly influence the brains hunger centers
Prescribing decisions should be individualised, considering the patient's specific needs, comorbidities, and treatment goals
[57] Semaglutide acts on these alterations by mitigating adipocyte hypertrophy and limiting excessive lipid storage through the downregulation of lipogenic enzymes such as lipoprotein lipase (LPL) and ANGPTL4
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