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This is one reason most IGF-1 LR3 protocols avoid late-evening dosing dosing close to bedtime is more likely to coincide with the natural overnight GH pulse
In the 72-week non-diabetic obesity trial, adults lost -15.0% at 5 mg, -19.5% at 10 mg, and -20.9% at 15 mg. Real-world outcomes vary because dose reached, adherence, and baseline state vary
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Because of this, their sourcing is easier to evaluate
Aim for 1,000-2,000mg of combined EPA/DHA daily
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