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Male C57BL/6J mice (3545 g, 15- to 23-weeks-old) fed HFD, HFD-32 (CLEA Japan, 57% of total calorie from fat), for 40100 days were used as the mouse model of diet-induced obesity
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The review evaluates these drugs across diverse patient populations, including those with clinically established T2D, obesity, CVD, and CKD