GPS has the ability to control the expression of genes that are involved in lipid metabolism, including peroxisome proliferator-activated receptor- (PPAR-) and sterol regulatory element-binding protein-1c (SREBP-1c)
Effect of ivermectin nanoformulations against nymphs The IVM spanlastics exhibited the highest acaricidal activity against nymphs, with mortality rates ranging from 40 to 93.3%, followed by IVM Se-NPs, which recorded mortality rates from 10 to 70%
Furthermore, nanocarriers can improve tissue uptake and distribution while reducing toxicity, making them an attractive delivery method for veterinary pest control 23,24,25,26
While studies have identified key regulators of GPX4-restricted LPO and cellular demise 1,2,6,12,13,14 , mechanism(s) of concurrent inflammatory responses remain elusive
Concomitantly, we measured increased pyruvate levels in mutant compared to control cells (Supplementary Fig