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Both Mounjaro and Ozempic may be prescribed off-label for weight loss, but the manufacturers warn against off-label uses

10.1152/jappl.1987.63.1.152 J Appl Physiol

But it may not be enough to establish the metabolic and behavioral changes needed for lasting results

However, no significant benefits were observed in nonglycemic laboratory outcomes and blood pressure, which could be attributed to the lack of abnormalities in participants at baseline