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Speak with an experienced physician through Apka Muaalij or call 042-32377001 to determine which therapy may be appropriate for you

MC1R is a G-protein-coupled receptor (GPCR) that, upon agonist engagement, activates the Gs/adenylate cyclase pathway, increasing intracellular cAMP and activating PKA-linked signalling cascades that upregulate tyrosinase activity and drive eumelanin synthesis the dark, UV-protective form of melanin

If diarrhoea becomes problematic, anti-diarrhoeal medications such as loperamide may provide relief, though you should discuss this with your GP first

M., Kang, D

it depends on your levels