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When NNMT activity is elevated as documented in obese adipose tissue, several cancer types, and aged skeletal muscle intracellular NAD+ availability decreases, SAM availability decreases, and downstream sirtuin activity (particularly SIRT1 and SIRT3) is reduced

B-12 supports DNA health, keeping your cells younger so you look and feel younger

These symptoms typically resolve within 24 hours.* Medical Considerations: Not suitable for individuals with known allergies to cobalamin, cardiovascular conditions, or chronic kidney disease