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To improve conceptual integration, key metabolic regulators, affected cell types, and therapeutic implications are summarized in schematic form (Figure 2) and comparative frameworks, facilitating a systems-level understanding of immunometabolic regulation in myocarditis

By significantly improving mitochondrial function within the energy-intensive cells of the intestinal lining (enterocytes) and simultaneously reducing local oxidative stress, ALCAR actively helps maintain **gut epithelial integrity**

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Diagnostic imaging and testing , including endoscopy reports, gastric-emptying studies, and lab data showing nutritional deficits or electrolyte abnormalities

Furthermore, effector genes GZMB , GNLY , GZMA , PRF1 , IL-2 , IFN as well as the master regulator of exhaustion TOX were significantly downregulated in rapamycin-treated CAR T products (Fig