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Cost-effectiveness of semaglutide in people with obesity and cardiovascular disease without diabetes

In the U.S., healthcare insurance is heavily subsidized by employers, whereas in countries with national healthcare systems, the employers contributions are more indirect

Severe vitamin B12 deficiency affects about 3 percent of adults in developed countries, but a more marginal deficiency may impact 26 percent, with the highest rates among adults older than 60

Comprehensive lifestyle modification should include dietary change to lower calorie intake, lifestyle and behavioral training, and increase physical activity

Cheaper does not mean safer to self-prescribe