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However, prolonged or high-dose ketamine exposure induces a compensatory upregulation of NMDARs, increasing intracellular calcium ion influx and ROS production, ultimately leading to neuronal apoptosis (Liu et al., 2013)
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Reduced appetite , which, while a therapeutic goal, may sometimes result in inadequate caloric intake if not monitored
Oesophageal cancer
Summary: B12 deficiency may be caused by malabsorption, poor dietary intake and/or pernicious anemia
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