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These treatments should only be performed by licensed and trained medical professionals using FDA-approved products and correct injection techniques
These drugs mimic a hormone and produce stimuli to the brain by binding to a receptor
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Besides GLP-1, DPP-4 also has other substrates and their elevation by DPP-4 inhibition can also contribute to a normalization of glycaemia in type 2 diabetes (indirect target or off-target) (10)
In these cardiovascular safety trials, in secondary or exploratory analyses, GLP-1 receptor agonists were also shown to reduce macro-albuminuria, an accepted surrogate marker for diabetic kidney disease (DKD), a condition that still represents a major unmet medical need
