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Assessing heat tolerance through productive vs physiological indicators
Following fixation and staining as above, coverslips were mounted on slides with ProLong Gold antifade (Invitrogen) and imaged using a VisiTech iSIM for super-resolution imaging (100x or 150x oil immersion objectives, Olympus)
Loy BD, Cameron MH, O'Connor PJ
The intricate imbalance between fatty acid and glucose oxidation, excessive succinate-driven ROS production, mitochondrial dysfunction, and Ca 2+ overload collectively drive cardiomyocyte death and adverse cardiac remodelling
