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Given that some included studies involved populations with diabetes, this increased risk may be related to prior or concomitant use of other glucose-lowering medications rather than an intrinsic effect of GLP-1 RAs
People with diabetes should avoid these formulations or account for the carbohydrate content in their meal planning
Strategies to optimise mineral balance and recovery during caloric restriction are discussed further in our guide to nutrient timing and interactions
This putative mechanism shares similarities with metformin, the first-line medication for type 2 diabetes, rather than with incretin-based therapies
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