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But you can only burn so much fat at once, and losing weight on the scale too quickly can come with a host of negative side effects: Fatigue or lightheadedness Nutrient deficiencies Dehydration Stress or irritability As well as muscle loss or wasting, which scientists call sarcopenia

For chronic weight management (Wegovy), the maintenance dose is 2.4 mg once weekly, reached through a more extended titration schedule: 0.25 mg for four weeks, 0.5 mg for four weeks, 1 mg for four weeks, 1.7 mg for four weeks, and finally 2.4 mg weekly

The authors thank the staff of the Community Medicine Research Center of Keelung Chang Gung Memorial Hospital