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The major sources of GLP-1 are the L-cells in the lining of small intestine
Cardiovascular data on endpoints like MACE-3 or MACE-4 are presently not available yet, but an early meta-analysis demonstrated at least cardiovascular safety in patients with T2D treated with tirzepatide (78, 79)
Br J Nutr 123(6):681690
What should I do if I can't tolerate the full dose of semaglutide
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