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Managing Appetite and Nausea When Combining Both Medications Tirzepatide causes appetite suppression and occasional nausea as expected GLP-1 effects, while some antidepressantsparticularly SSRIscan independently affect appetite in either direction

When blood sugar stays more stable throughout the day, patients frequently report steadier energy levels and a reduced desire to reach for sugary or high-carbohydrate snacks

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Other normal purging signs include mild dryness or flaking as dead cells shed more rapidly, temporary sensitivity that remains manageable, and brief periods of dullness before radiance emerges

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