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For the side effect phenotypes, we defined separate casecontrol phenotypes for each side effect recorded in the survey, contrasting those who self-rated their side effects as moderate or severe (cases) to those who self-rated their side effects as mild or non-existent (controls)

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Glutathione is a naturally occurring tripeptide composed of glycine, cysteine, and glutamic acid and plays a role in cellular antioxidant activity and detoxification processes

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Electrophilic bromination often yields dibrominated quinoxaline, as the activated benzene ring overreacts, reducing target yield