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Some patients experience mild side effects such as nausea, bloating, or constipation , but these symptoms typically subside as the body adapts
10.21037/atm.2020.02.36 Ann
Eat Balanced Meals Regularly : skipping meals or undereating can worsen cold sensitivity
1 Intensive insulin therapy, necessary for optimal glucose management, often drives further weight gain, creating a challenging clinical cycle
Despite this gap in knowledge, a plausible hypothesis could be formulated that either treatment with exogenous melatonin or interventions aimed at restoring endogenous melatonin secretion might offer potential in mitigating neurodegenerative processes induced by circadian disruption
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