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Advanced glycation end products as biomarkers and gerontotoxins a basis to explore methylglyoxal-lowering agents for Alzheimer's disease

However, the addition of trisomy 21 in the first case, and raised adenosine in the second, brings the profiles much closer to those observed in patients with Down syndrome and autism, respectively

mRFP-GFP-LC3 is a ratiometric probe bound to both the inner and outer membrane of the autophagosome 33

Hernantz A, Fernandez-Vivancos E, Montiel C, Vazquez JJ, Arnalich S: Changes in the intracellular homocysteine and glutathione content associated with aging

Conditioned medium was harvested, filtered through 0.45-m filters, concentrated by ultracentrifugation (81550 g, 2 h at 4 C) and stored at 80 C