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**Gastrointestinal Discomfort**: One of the most frequently reported side effects is gastrointestinal discomfort
This documentation helps identify patterns if research results seem inconsistent
This approach is best exemplified by targeting two or three class B1 G protein-coupled receptors, namely, glucagon-like peptide-1 receptor (GLP-1R), glucagon receptor (GCGR) and glucose-dependent insulinotropic polypeptide receptor for treatment of type 2 diabetes and obesity
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