This indicates that its proliferative and cytoprotective effects on the gut epithelium are mediated indirectly via paracrine signaling ( GLP-2 is recognized as a key intestinal growth factor capable of enhancing mucosal proliferation, improving nutrient absorption, and maintaining gut barrier integrity ( Dipeptidyl peptidase IV DPP-IV, also known as CD26, is a serine protease that degrades both GLP-1 and GLP-2
Moreover, individuals with diabetes require continuous monitoring to prevent acute complications such as hypoglycemia and diabetic ketoacidosis
On the basis of the differences in the gradients, an average relative biopotency of 14.8% could be inferred for intestinal administration over the full dose range, albeit with this likely to be higher if assessing only lower doses
Patients should remain seated for a few minutes after an IM or IV dose, just to ensure they do not experience dizziness
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