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FA group D2 protein (FANCD2)-mediated DNA repair inhibits erastin-induced ferroptosis in bone marrow cells (Song et al

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showed that ARID1A-deficient cancer cells expressed low levels of the key cystine transporter SLC7A11 and thus exhibited low basal levels of GSH, which made these cancer cells specifically vulnerable to inhibition of the GSH metabolic pathway 25

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However, cycling prevents potential receptor desensitization, allows natural healing integration, reflects a conservative approach given limited long-term human data, and reduces cost

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Following the generation of acetyl-CoA by pyruvate dehydrogenase (PDH), acetyl-CoA condenses with oxaloacetate to form citrate

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