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NAPQI is a strong oxidising agent and has the potential to cause liver and kidney damage by reacting with cellular and mitochondrial proteins [21]
Researchers had been finding GLP-1 receptors in places outside the pancreas including the vagal nerve, which connects the gut to the brain
& Barral, D
Conclusions and Recommendations Key messages for at-risk populations: The EVOKE trial failure does not invalidate GLP-1 agonists for preventionthe epidemiological signal remains strong, and these drugs may provide metabolic and cardiovascular benefits with potential cognitive co-benefits when used for approved indications SS-31s approval establishes precedent for mitochondrial-targeted therapeuticswatch this space for expanded indications Popular biohacker peptides (BPC-157, Dihexa, P21) have essentially no human cognitive evidence
